Florida KeysBoutique Hotels with Spa

List Of Best Boutique Hotels with Spa Florida Keys

We have created a list with the best boutique hotels with spa in Florida Keys, USA. Hope you enjoy it. We think it might be the best of its kind around

boutique hotels in Florida Keys
Hotel
526 Angela Street, Downtown Key West, Key West, FL 33040, USA

Welcome to our adult-only hotel in beautiful Key West, Florida! Here, you can relax and unwind by enjoying our two refreshing outdoor pools. If you're looking to explore the vibrant atmosphere of Duval Street, it's just a quick 1-minute stroll from our front door. Additionally, the enchanting Key West Butterfly and Nature Conservatory is only a 3-minute drive away, perfect for a peaceful day surrounded by nature. We look forward to making your stay enjoyable and memorable!

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  • Oceanfront
    Oceanfront
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
  • Highly Rated
    Highly Rated
  • Ocean View
10 Baths374.34 ft²
9.2

Exceptional

112 reviews

$483.92
Average price / night
Check Availability
boutique hotels in Florida Keys
Resort
99010 Overseas Highway Mile Marker 99 Bayside, Key Largo, FL 33037, USA

Welcome to our beautiful resort in Key Largo, designed exclusively for adults 21 and over. Here, you can unwind in cozy bungalows, enjoy a serene private beach, and participate in daily yoga sessions that cater to all skill levels. Savor delicious meals at our four on-site restaurants, take a refreshing dip in one of our two outdoor pools, or relax in our inviting jacuzzis. We offer a full-service experience to ensure your stay is comfortable and enjoyable. Your relaxation and happiness are our top priorities, and we can't wait to welcome you!

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  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Frequently Viewed
    Frequently Viewed
  • Ocean View
5 Baths904.17 ft²
8.8

Exceptional

185 reviews

$1205.67
Average price / night
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boutique hotels in Florida Keys
Resort
97450 Overseas Highway, Key Largo, FL 33037, USA

At Playa Largo Resort & Spa, we offer a warm and welcoming experience with 155 luxurious accommodations that invite you to enjoy the sunshine and stunning sunsets over Florida Bay. As the first new resort built in the Florida Keys in over 23 years, we are excited to provide a beautiful getaway for all guests. Whether you're looking for relaxation or adventure, our resort is designed to be a place where everyone can feel at home and create lasting memories.

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  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
17 Baths797.8 ft²
8.6

Exceptional

388 reviews

$392
Average price / night
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boutique hotels in Florida Keys
Resort
245 Front Street, Downtown Key West, Key West, 33040, USA

Welcome to our waterfront hotel in the heart of Old Town, Key West, Florida! Here, you’ll find a relaxing outdoor heated pool and hot tub, perfect for unwinding after a day of exploring. Plus, we're right next to the Key West Aquarium, making it easy for you to enjoy some marine fun. Each room is equipped with a cable TV for your entertainment. We’re excited to help make your stay enjoyable and memorable!

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  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
  • Fireplace/Heating
    Fireplace/Heating
27 Baths631.16 ft²
8.6

Exceptional

1135 reviews

$472.33
Average price / night
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boutique hotels in Florida Keys
Resort
400 South Collier Boulevard, Marco Island, FL 34145, USA

Welcome to our beautiful resort on Marco Island, where you can escape the everyday hustle and enjoy a truly memorable experience. Whether you're here for work or a vacation, we have something special for everyone. Treat yourself at our luxurious spa, designed to help you relax and rejuvenate. We can't wait to welcome you and make your stay enjoyable!

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  • Private Beach
    Private Beach
  • Oceanfront
    Oceanfront
  • Hot Tub
    Hot Tub
  • Spa
    Spa
7 Baths398.26 ft²
8.6

Exceptional

302 reviews

$529
Average price / night
Check Availability

Compare the Best Boutique Hotels with Spa in Florida Keys – Addresses, Prices, Stars, Rating, and Review Count

Hotel Name Address Price ($)Star Rating Review Count Book
The Gardens Hotel526 Angela Street, Downtown Key West, Key West, FL 33040, USA483.9249.2112
Bungalows Key Largo - All Inclusive99010 Overseas Highway Mile Marker 99 Bayside, Key Largo, FL 33037, USA1205.6748.8185
Playa Largo Resort & Spa, Autograph Collection97450 Overseas Highway, Key Largo, FL 33037, USA39258.6388
Opal Key Resort & Marina245 Front Street, Downtown Key West, Key West, 33040, USA472.3348.61135
JW Marriott Marco Island Beach Resort400 South Collier Boulevard, Marco Island, FL 34145, USA52948.6302

Note: The prices for each boutique hotels in Florida Keys do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.

Top 8 Attractions in Florida Keys, USA

Luxury or Boutique stay in Florida Keys, USA: As you explore this stunning destination, you're bound to discover an array of attractions that perfectly complement your luxurious getaway.

Duval Street: This lively street is the heart of Key West, filled with vibrant shops, art galleries, and inviting restaurants that offer a taste of local culture and nightlife.

John Pennekamp Coral Reef State Park: Experience the underwater wonderland of the first underwater park in the U.S., where snorkeling and diving unveil breathtaking coral reefs teeming with marine life.

Ernest Hemingway Home and Museum: Step into the world of literary great Ernest Hemingway by visiting his former residence, adorned with unique architecture and lush gardens that inspire creativity.

Key Largo's African Queen: Relive history aboard the famous steamboat from the classic film, offering sightseeing tours that showcase the area's enchanting waterways.

Dry Tortugas National Park: Embark on a ferry ride to this remote paradise, where you can explore historic Fort Jefferson and indulge in pristine beaches and exceptional snorkeling opportunities.

The Dolphin Research Center: Spend a day interacting with dolphins and learning about their behaviors at this educational facility, which promotes wildlife conservation and animal care.

Sunset Celebration at Mallory Square: Witness breathtaking sunsets while enjoying live entertainment, local artisans, and delightful cuisine at this iconic gathering spot in Key West.

Florida Keys Eco-Discovery Center: Dive into the unique ecosystems of the Florida Keys through engaging exhibits and interactive displays that highlight the importance of marine preservation.

Frequently Asked Questions

Transportation/Shuttle service is available at the following boutique hotels in Florida Keys: