
Welcome to Depot Inn & Suites, where we celebrate the charm of the 1800s railroad era. Our hotel is designed to make you feel at home while surrounded by fascinating pieces of railroad history. Think of it as a cozy museum that tells the story of the railroads, inviting you to explore and enjoy the unique decor. We aim to create a warm and welcoming atmosphere for everyone who visits. Come experience our blend of comfort and history in a setting that honors the past while catering to your needs.
Exceptional
333 reviews

The Merrill Hotel in Muscatine, Iowa, is a unique and welcoming place to stay. Nestled in the heart of downtown and right by the beautiful Mississippi River, this boutique hotel offers a special experience for everyone who visits. With its 4 Diamond rating, it combines comfort with thoughtful service, ensuring that each guest feels valued and at home. Whether you’re here for business, leisure, or a little bit of both, we invite you to discover all that The Merrill has to offer.
Exceptional
53 reviews

Welcome to our hotel, conveniently situated at Water Tower Park, just a short stroll from Michigan Avenue. If you love art, you’ll be pleased to know that the Museum of Contemporary Art is only a 5-minute walk away. We are committed to making your stay comfortable and enjoyable, and we are here to help with anything you may need during your time with us. Whether you're exploring the city or relaxing in our welcoming space, we look forward to being a part of your journey!
Exceptional
238 reviews

Welcome to our welcoming 4-star hotel in downtown Milwaukee, where your comfort is our priority! Here, you can enjoy a full-service spa and salon, perfect for relaxation and self-care. We also have a beautiful collection of Victorian art that adds charm to our space. If you're an art lover, you'll be pleased to know that the renowned Milwaukee Art Museum is just a short 10-minute stroll away. Plus, we offer complimentary WiFi throughout the hotel so you can stay connected during your visit. We look forward to making your stay enjoyable and memorable!
Exceptional
774 reviews

The Langham Chicago is designed to make you feel at home in the heart of the city. Here, you'll find a perfect mix of modern comfort and elegant style. We focus on providing thoughtful amenities and high-quality details that ensure your stay is both enjoyable and relaxing. Whether you're visiting for business or leisure, our goal is to create a welcoming environment where you can unwind and feel valued.
Exceptional
333 reviews

If you're planning a visit to Chicago, consider staying at the Nobu Hotel Chicago, located just a short 1.5 km from Union Station. This hotel offers a welcoming atmosphere with a cozy bar and convenient private parking for guests. You can enjoy delicious meals at their on-site restaurant and maintain your fitness routine at the well-equipped fitness center. Whether you’re traveling for business or leisure, the Nobu Hotel aims to make your stay comfortable and enjoyable.
Exceptional
375 reviews

Located just a short walk from Van Andel Arena and Devos Hall, the Residence Inn by Marriott Grand Rapids Downtown offers comfortable rooms equipped with air conditioning and private bathrooms. Whether you're here for a concert, event, or just exploring the city, our welcoming space is designed to make your stay enjoyable and convenient. We prioritize your comfort and aim to provide a friendly environment that feels like home.
Exceptional
491 reviews

Welcome to Comfort Suites in Grand Island! We’re excited to offer you a comfortable stay with free WiFi throughout the hotel. You can relax and unwind in our indoor pool, stay active at our fitness center, and rest easy knowing our friendly staff is available at our 24-hour front desk to assist you whenever you need. Each of our rooms comes equipped with a refrigerator, making it easy for you to store snacks and drinks during your visit. We look forward to making your stay enjoyable!
Exceptional
299 reviews

Welcome to the Park Hyatt Chicago, nestled in the vibrant Gold Coast neighborhood of downtown Chicago. Here, you’ll find a warm and welcoming atmosphere where sophistication meets comfort. Our hotel is not just about luxury; it's about creating memorable experiences for everyone who walks through our doors. We take pride in showcasing beautiful art and providing modern amenities that cater to your needs. Whether you're visiting for business or leisure, our friendly staff is here to ensure you feel at home and have everything you need for a pleasant stay. We look forward to welcoming you!
Exceptional
86 reviews

Welcome to our Branson resort, where we invite you to relax and enjoy the beautiful surroundings of Table Rock Lake. We have a private boat dock for your convenience, as well as indoor and outdoor pools for you to splash around in or simply unwind. Our spacious apartments come equipped with everything you need for a comfortable stay, including a private deck where you can take in the stunning views and a full kitchen for preparing meals with family and friends. And when the evenings cool down, gather around the cozy wood-burning fireplace for warmth and connection. We can’t wait to welcome you and help you create wonderful memories here!
Exceptional
101 reviews

Just a short walk of 500 meters from the Sioux City Convention Centre, The Warrior Hotel, part of the Autograph Collection, welcomes guests to enjoy its comfortable 4-star accommodations. Guests can relax at the on-site bar or dine at the restaurant, which offers a variety of delicious options. Whether you’re here for business or leisure, our dedicated team is ready to make your stay enjoyable and memorable.
Exceptional
202 reviews

Experience breathtaking views from every corner of our hotel, a remarkable 92-story building made of stainless steel and tinted glass. Situated along the Chicago River, right by the Loop and North Michigan Avenue, our landmark offers a welcoming space where everyone can feel at home while enjoying the beauty of the city. Whether you’re here for business or pleasure, we strive to create an atmosphere that caters to your needs and enhances your stay.
Exceptional
1289 reviews

Welcome to the newly opened Loews Chicago in the vibrant Streeterville neighborhood! Our hotel offers a comfortable stay with 400 guest rooms and 25 spacious suites, perfect for families, business travelers, and anyone seeking a relaxing getaway. At our lobby bar, ETA, you can unwind with a drink or snack, while Chef Jose Garces’ Rural Society invites you to enjoy delicious meals inspired by local flavors. For those planning events, we have expansive meeting spaces designed to accommodate gatherings of all sizes. After a busy day, take some time for yourself at our luxurious spa, where you can indulge in rejuvenating treatments. We look forward to welcoming you and ensuring your experience is enjoyable and memorable!
Exceptional
1230 reviews

Welcome to Old Kinderhook! Here, we invite you to experience a wonderful getaway that offers something for everyone. Whether you're a golf enthusiast looking to play on our championship courses, someone who enjoys delicious dining options, or simply seeking relaxation at our on-site spa, you'll find plenty of ways to unwind and have fun. For those planning meetings or special events, our flexible meeting spaces span over 11,000 square feet, making it easy to create the perfect setting for any occasion. Plus, our beautiful surroundings in Central Missouri provide a stunning backdrop for your visit. We look forward to welcoming you to Old Kinderhook, where your comfort and enjoyment are our top priorities!
Exceptional
29 reviews

Welcome to our Hilton hotel in Columbus, Ohio! We're conveniently located just a short 11-minute drive from Port Columbus International Airport, making your travel experience smoother. If you're visiting Ohio State University, it's only about 2 miles away, so you'll find it easy to reach campus. Our hotel is not just a place to stay; it also showcases beautiful artwork throughout the property, creating a welcoming and inspiring atmosphere for all guests. We're here to ensure you have a comfortable and enjoyable experience during your stay with us!
Exceptional
582 reviews

Welcome to SpringHill Suites by Marriott Overland Park Leawood! We're excited to offer a comfortable and welcoming space for you to relax and enjoy your stay. Located in the beautiful Overland Park area of Kansas, we are conveniently close to various attractions, just a short drive from downtown Kansas City, where you can explore the Kansas City Convention Center and the National World War I Museum. Our hotel features a cozy bar where you can unwind with friends or family after a day of exploring. We prioritize creating a warm and friendly atmosphere to ensure that everyone feels at home during their visit. We look forward to welcoming you and making your stay enjoyable!
Exceptional
80 reviews






Note: The prices for each boutique hotels in Midwest do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here>) to get the latest prices.
Luxury or Boutique stay in Midwest, USA: The Midwest offers an array of attractions that complement your elegant getaway, ensuring that every moment is filled with excitement and wonder.
Gateway Arch: Stand in awe at the iconic Gateway Arch in St. Louis, Missouri, where you can take a tram ride to the top for breathtaking views of the city skyline and the Mississippi River.
Badlands National Park: Explore the striking landscapes of Badlands National Park in South Dakota, known for its dramatic rock formations and unique wildlife that make for unforgettable hikes and photography opportunities.
Lake Michigan: Enjoy a refreshing day at Lake Michigan's stunning shorelines, where you can relax on beautiful beaches, indulge in water sports, or simply revel in picturesque sunsets.
The Henry Ford Museum: Discover American innovation at The Henry Ford Museum in Dearborn, Michigan, which showcases artifacts from the automotive industry and significant moments in U.S. history.
Minnehaha Falls: Experience the serene beauty of Minnehaha Falls in Minneapolis, Minnesota, where you can stroll through scenic park trails and marvel at cascading waterfalls amidst lush greenery.
Cincinnati Zoo & Botanical Garden: Visit the Cincinnati Zoo & Botanical Garden, one of the oldest zoos in the U.S., offering a delightful day filled with exotic animals and beautiful botanical displays.
Indiana Dunes National Park: Unwind at Indiana Dunes National Park along the southern shores of Lake Michigan, where sandy beaches, hiking trails, and diverse ecosystems await nature enthusiasts and adventurers alike.
Popular boutique hotels in Midwest that have a pool include:
Transportation/Shuttle service is available at the following boutique hotels in Midwest:
A spa is available to guests at the following boutique hotels in Midwest:
Families traveling in Midwest enjoyed their stay at the following boutique hotels:
These 3 star hotels received great reviews from other travelers:
Some of the best boutique hotels in Midwest are: